When did nice become an insult, and simple such a burden? Pádraic Súilleabháin (Colin Farrell) is a nice man, leading a simple life on the fictional island of Inisherin, just off the coast of Ireland. The year is 1923. Even as a civil war rages across the water, for Pádraic all is well in the world so long as he gets to meet his lifelong friend, Colm Doherty (Brendan Gleeson), at the pub at 2 pm every day for a pint. When Colm fails to arrive one day – and then refuses to come at all – Pádraic’s blissfully straightforward existence is thrown askew. Before long, Colm announces his intention to sever his relationship with Pádraic entirely, threatening a series of escalating (and gruesome) consequences should he not respect his wishes.